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Image Search Results
Figures S2 and . " width="100%" height="100%">
Journal: Cell Reports Methods
Article Title: Generation of dual-attribute iTNK cells from hPSCs for cancer immunotherapy
doi: 10.1016/j.crmeth.2024.100843
Figure Lengend Snippet: Expression of T cell signature genes in hPSC-derived T lineage cells (A) Uniform manifold approximation and projection (UMAP) representation of the T56 ATO T cell induction system containing T lineage, ILC lineage, mast cell lineage, and a small number of undefined clusters that did not resemble any in vivo cell type. Results from the hESC line H1 are shown. (B) Lineage-specific marker gene expression patterns in each cluster. (C) TCR + and TCR − cell distributions in the T56 ATO T cell induction system. (D) T cell signature and NK cell signature gene expression patterns in TCR + cells from the T56 ATO T cell induction system. See also
Article Snippet:
Techniques: Expressing, Derivative Assay, In Vivo, Marker, Gene Expression
Figures S4 and . " width="100%" height="100%">
Journal: Cell Reports Methods
Article Title: Generation of dual-attribute iTNK cells from hPSCs for cancer immunotherapy
doi: 10.1016/j.crmeth.2024.100843
Figure Lengend Snippet: Expression of typical T cell signature genes and NK cell signature genes in hPSC-derived iTNK cells (A) TCR + and TCR − cell distributions in hPSC-derived iTNK cells. Results from the hESC line H1 are shown. (B) Lineage-specific marker gene expression patterns in TCR + and TCR − cells. (C) T cell signature and NK cell signature gene expression patterns in TCR + iTNK cells. See also
Article Snippet:
Techniques: Expressing, Derivative Assay, Marker, Gene Expression
Figures S6–S8 . " width="100%" height="100%">
Journal: Cell Reports Methods
Article Title: Generation of dual-attribute iTNK cells from hPSCs for cancer immunotherapy
doi: 10.1016/j.crmeth.2024.100843
Figure Lengend Snippet: TCR repertoires and differences in expression of hPSC-derived T lineage cells and iTNK cells (A) CDR3 length distributions of hPSC-derived T lineage cells. Results from the hESC line H1 are shown. (B) CDR3 length distributions of hPSC-derived iTNK cells. Results from the hESC line H1 are shown. (C) TCR V-gene usage among hPSC-derived T lineage cells. (D) TCR V-gene usage among hPSC-derived iTNK cells. (E) Gene Ontology enrichment of upregulated genes in TCR + iTNK cells compared with TCR + T lineage cells. (F) Trajectory analysis of the cells in ATO system and iTNK cells. See also
Article Snippet:
Techniques: Expressing, Derivative Assay
Journal: Cell Reports Methods
Article Title: Generation of dual-attribute iTNK cells from hPSCs for cancer immunotherapy
doi: 10.1016/j.crmeth.2024.100843
Figure Lengend Snippet:
Article Snippet:
Techniques: Staining, Purification, Recombinant, Modification, Membrane, Cell Stimulation, Wright Stain, Software